circRNA basic information
circBase ID: hsa_circ_0000376
Name: hsa_circ_PRH1-PRR4
Synonym: -
Host Gene: hsa-miR-182
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human normal breast cell line (MCF10A), BC cell lines (MDA-MB-231 , MDA-MB-157, SUM-159, MCF-7,SK-BR-3)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ZFP36
Associated microRNA: hsa-miR-182
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 2
Description:

circRNA_000554 functioned as an inhibitor of EMT in BC and suggests a molecular mechanism that circRNA_000554 bound to miR-182 to upregulate ZFP36 in this process.
Other information
Title:

Circular RNA 000554 represses epithelial-mesenchymal transition in breast cancer by regulating microRNA-182/ZFP36 axis.

Journal: FASEB J
Published: 2020/7/31
PubMed ID: 32729957