circRNA basic information
circBase ID: -
Name: hsa_circ_CCNB2
Synonym: Circ_CCNB2
Host Gene: hsa-miR-30b-5p
 
 
 
Disease basic information
DO ID:
 10283
DO name: prostate cancer
Disease details: prostate cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human PCa cell lines (DU145, LNCaP)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: KIF18A
Associated microRNA: hsa-miR-30b-5p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

knockdown of circ_CCNB2 was shown to promote PCa radiosensitivity through autophagy repression by miR-30b-5p/KIF18A axis, developing a molecular resistance mechanism of PCa radiotherapy and a feasible strategy to increase radiosensitivity.
Other information
Title:

Knockdown of Circ_CCNB2 Sensitizes Prostate Cancer to Radiation Through Repressing Autophagy by the miR-30b-5p/KIF18A Axis.

Journal: Cancer Biother Radiopharm
Published: 2020/7/28
PubMed ID: 32716640