circRNA basic information
circBase ID: hsa_circ_0000735
Name: hsa_circ_P2RX1
Synonym: -
Host Gene: hsa-miR-7
 
 
 
Disease basic information
DO ID:
 10283
DO name: prostate cancer
Disease details: prostate cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: PCa cell lines (PC-3, DU145), normal human prostatic epithelial cells (RWPE-1)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-7
Biological function: -
Molecular mechanism: miRNA sponge
Survival: poor
Supported No.:
 1
Description:

Hsa_circ_0000735 downregulation boosted PCa sensitivity to DTX and reduced tumor growth via sponging miR-7, providing a promising prognostic biomarker and therapeutic target for PCa.
Other information
Title:

Downregulation of circular RNA hsa_circ_0000735 boosts prostate cancer sensitivity to docetaxel via sponging miR-7.

Journal: Cancer Cell Int
Published: 2020/7/28
PubMed ID: 32714093