circRNA basic information
circBase ID: hsa_circ_0017311
Name: hsa_circ_CNST
Synonym: -
Host Gene: hsa-miR-421
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: normal bone tissues, OS cell lines (MG-63, SW1353, 143B, Saos-2, HOS, U-2OS)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: SLC25A3
Associated microRNA: hsa-miR-421
Biological function: Knockdown of circCNST repressed cell viability, colony formation, and xenograft tumor growth
Molecular mechanism: acted as a sponge of hsa-miR-421
Survival: -
Supported No.:
 2
Description:

circCNST promotes the tumorigenesis of OS cells by sponging miR-421, and provides a potential biomarker for patients with OS.
Other information
Title:

Circular RNA_CNST Promotes the Tumorigenesis of Osteosarcoma Cells by Sponging miR-421.

Journal: Cell Transplant
Published: 2020/7/23
PubMed ID: 32693639