circRNA basic information
circBase ID: -
Name: -
Synonym: circRNA-103809
Host Gene: hsa-miR-1270
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: cell line
Sample type details: human normal liver cell (HL7702), liver cancer cells (MHCC97H, HepG2, Huh7, SMMC7721)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: PLAGL2
Associated microRNA: hsa-miR-1270
Biological function: After interfering circRNA-103809, the proliferation, migration, invasion and epithelial-to-mesenchymal transition process were all hindered in HCC cells
Molecular mechanism: competed with PLAG1 like zinc finger 2 (PLAGL2) for binding with microRNA-1270 (hsa-miR-1270)
Survival: -
Supported No.:
 1
Description:

Hsa-circRNA-103809 promoted development of HCC via sequestering miR-1270 and up-regulating PLAGL2.
Other information
Title:

Hsa-circRNA-103809 Promotes Hepatocellular Carcinoma Development via MicroRNA-1270/PLAG1 Like Zinc Finger 2 Axis.

Journal: Dig Dis Sci
Published: 2020/7/20
PubMed ID: 32683589