circRNA basic information
circBase ID: -
Name: hsa_circ_HECTD1
Synonym: -
Host Gene: hsa-miR-485-5p
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: normal liver cell (THLE-3), liver cancer cell lines (HCCLM, MHCC97L, SMMC7721-1640, Hep3B, HepG2)
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: MUC1
Associated microRNA: hsa-miR-485-5p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

circHECTD1 facilitates HCC progression by sponging miR-485-5p to up-regulate MUC1.
Other information
Title:

CircHECTD1 up-regulates mucin 1 expression to accelerate hepatocellular carcinoma development by targeting microRNA-485-5p via a competing endogenous RNA mechanism.

Journal: Chin Med J (Engl)
Published: 2020/7/18
PubMed ID: 32675746