circRNA basic information
circBase ID: hsa_circ_0007766
Name: hsa_circ_ERBB2
Synonym: -
Host Gene: hsa-miR-1233-3p
 
 
 
Disease basic information
DO ID:
10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human gastric cancer cell lines (SNU-216, HGC-27, BGC-823, SGC-7901), human gastric epithelial cell line (GES-1)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: GDF15
Associated microRNA: hsa-miR-1233-3p
Biological function: Knock-down of hsa-circ-0007766 inhibited cell proliferation, migration, invasion
Molecular mechanism: via hsa-circ-0007766/hsa-miR-1233-3p/GDF15 axis
Survival: -
Supported No.:
2
Description:

This study unveils a mechanism by which hsa-circ-0007766 regulates GDF15 via hsa-circ-0007766/miR-1233-3p/GDF15 axis, which may provide new insight for GC therapeutic strategies.

Other information
Title:

Circular RNA hsa-circ-0007766 modulates the progression of Gastric Carcinoma via miR-1233-3p/GDF15 axis.

Journal: Int J Med Sci
Published: 2020/7/17
PubMed ID: 32669960