circRNA basic information
circBase ID: hsa_circ_0002755
Name: hsa_circ_CLIP2
Synonym: -
Host Gene: hsa-miR-628-5p
 
 
 
Disease basic information
DO ID:
0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: normal human astrocytes (NHA), human glioma cell lines (A-172, SHG-44)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: MAGT1
Associated microRNA: hsa-miR-628-5p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
3
Description:

overexpression of circ_0002755 overturned Sev-mediated inhibitory effect on glioma progression. Further research indicated that circ_0002755 targeted miR-628-5p, and miR-628-5p targeted MAGT1, and Sev modulated glioma progression via circ_0002755/miR-628-5p/MAGT1 axis. Moreover, Sev hindered tumor growth in vivo.

Other information
Title:

Sevoflurane Regulates Glioma Progression by Circ_0002755/miR-628-5p/MAGT1 Axis.

Journal: Cancer Manag Res
Published: 2020/7/17
PubMed ID: 32669871