circRNA basic information
circBase ID: -
Name: hsa_circ_LDLRAD3
Synonym: -
Host Gene: hsa-miR-137
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: NSCLC cell lines (A549, H1299, Calu-3), human bronchial epithelial cell line (HBE)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: SLC1A5
Associated microRNA: hsa-miR-137
Biological function: knock-down of circ-LDLRAD3 and miR-137 overexpression promoted NSCLC cell apoptosis, and inhibited cell proliferation and invasion
Molecular mechanism: regulating hsa-miR-137/SLC1A5 axis
Survival: -
Supported No.:
 1
Description:

knock-down of circ-LDLRAD3 inhibited the development of NSCLC by regulating miR-137/SLC1A5 axis.
Other information
Title:

Circular RNA circ-LDLRAD3 serves as an oncogene to promote non-small cell lung cancer progression by upregulating SLC1A5 through sponging miR-137.

Journal: RNA Biol
Published: 2020/7/14
PubMed ID: 32658600