circRNA basic information
circBase ID: -
Name: hsa_circ_FOXO3
Synonym: -
Host Gene: hsa-miR-9-5p
 
 
 
Disease basic information
DO ID:
 11054
DO name: urinary bladder cancer
Disease details: bladder cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: bladder cancer cell lines (EJ, T24)
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
DN
Associated gene: TGFBR2
Associated microRNA: hsa-miR-9-5p
Biological function: inhibited cell proliferation, migration and invasion
Molecular mechanism: regulates TGFBR2 expression through sponging hsa-miR-9-5p
Survival: -
Supported No.:
 2
Description:

circ-FOXO3 was significantly down-regulated in bladder cancers. circ-FOXO3 overexpression inhibits BC cell progression and metastasis. Furthermore, circ-FOXO3 regulates TGFBR2 expression through sponging miR-9-5p in BC cell lines.
Other information
Title:

Circular RNA FOXO3 Suppresses Bladder Cancer Progression and Metastasis by Regulating MiR-9-5p/TGFBR2.

Journal: Cancer Manag Res
Published: 2020/7/3
PubMed ID: 32612392