circRNA basic information
circBase ID: -
Name: hsa_circ_DOCK1
Synonym: -
Host Gene: hsa-miR-124
 
 
 
Disease basic information
DO ID:
 1781
DO name: thyroid gland cancer
Disease details: thyroid cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: thyroid cancer cell lines (FTC-133, TPC-1)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: signaling transduction of JAK/STAT/AMPK
Associated microRNA: hsa-miR-124
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

circDOCK1 contributed to thyroid carcinogenesis through inhibition of miR-124 in thyroid cancer cells with dampening signaling transduction of JAK/STAT/AMPK in virtue of miR-124 downregulation.
Other information
Title:

Circular RNA DOCK1 downregulates microRNA-124 to induce the growth of human thyroid cancer cell lines.

Journal: Biofactors
Published: 2020/6/26
PubMed ID: 32584497