circRNA basic information
circBase ID: hsa_circ_0064574
Name: hsa_circ_RPL15
Synonym: -
Host Gene: hsa-miR-502-3p
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: normal gastric epithelial cell line (GES-1) and GC cell lines (MGC-803, BGC-823, MKN-28, SGC-7901, AGS)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: OLFM4/STAT3
Associated microRNA: hsa-miR-502-3p
Biological function: promoted the proliferation, migration and invasion of GC cells and inhibited apoptosis
Molecular mechanism: sponging hsa-miR-502-3p and activated OLFM4/STAT3 pathway
Survival: poor
Supported No.:
 1
Description:

circ-RPL15 promotes GC progression and predicts poor prognosis of GC patients, and regulates the malignant phenotypes of GC cells by mediating the miR-502-3p/OLFM4/STAT3 axis.
Other information
Title:

Overexpressed circ-RPL15 predicts poor survival and promotes the progression of gastric cancer via regulating miR-502-3p/OLFM4/STAT3 pathway.

Journal: Biomed Pharmacother
Published: 2020/6/21
PubMed ID: 32559850