circRNA basic information
circBase ID: hsa_circ_0027345
Name: hsa_circ_LRIG3
Synonym: -
Host Gene: hsa-miR-345-5p
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: cell line, PDX
Sample type details: human HCC cell lines (Huh-7, HCCLM3)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: HOXD3
Associated microRNA: hsa-miR-345-5p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 3
Description:

Matrine inhibited cell development and tumorigenesis in HCC by increasing miR-345-5p and decreasing circ_0027345 and HOXD3.
Other information
Title:

Matrine inhibits cell growth, migration, invasion and promotes autophagy in hepatocellular carcinoma by regulation of circ_0027345/miR-345-5p/HOXD3 axis.

Journal: Cancer Cell Int
Published: 2020/6/19
PubMed ID: 32549793