circRNA basic information
circBase ID: hsa_circ_0007444
Name: -
Synonym: circ_0007444
Host Gene: hsa-miR-570-3p
 
 
 
Disease basic information
DO ID:
 2394
DO name: ovarian cancer
Disease details: ovarian cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: SKOV3, OV420, A2780, CAOV3, OVCAR3
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: PTEN
Associated microRNA: hsa-miR-570-3p
Biological function: promoted PTEN expression via sponging miR-570-3p
Molecular mechanism: inhibited proliferation, migration, and invasion, and promoted apoptosis
Survival: better
Supported No.:
 2
Description:

circ_0007444 is a tumor suppressor in OC, which inhibits OC progression by mediating the miR-570-3p/PTEN. circ_0007444 can be a potential candidate for targeted therapy of OC.
Other information
Title:

Circ_0007444 Inhibits the Progression of Ovarian Cancer via Mediating the miR-570-3p/PTEN Axis.

Journal: Onco Targets Ther
Published: 2021/1/15
PubMed ID: 33442269