circRNA basic information
circBase ID: hsa_circ_0003506
Name: hsa_circ_CYFIP2
Synonym: -
Host Gene: hsa-miR-1205
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: normal gastric mucosa epithelial cell line (GES-1), human GC cell lines (MKN-28, AGS, MKN-45, BGC-823, MGC-803, HGC-27, SGC-7901)
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: E2F1
Associated microRNA: hsa-miR-1205
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 2
Description:

circCYFIP2 might serve as an oncogenic circRNA to promote GC progression via the miR-1205/E2F1 axis, which provided a potential therapeutic target for the treatment of GC.
Other information
Title:

circCYFIP2 Acts as a Sponge of miR-1205 and Affects the Expression of Its Target Gene E2F1 to Regulate Gastric Cancer Metastasis.

Journal: Mol Ther Nucleic Acids
Published: 2020/6/12
PubMed ID: 32526476