circRNA basic information
circBase ID: hsa_circ_0001681
Name: hsa_circ_RAPGEF5
Synonym: -
Host Gene: hsa-miR-942-5p
 
 
 
Disease basic information
DO ID:
 1781
DO name: thyroid gland cancer
Disease details: thyroid cancer
Species: human
Species details: human
Sample type: cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: TWIST1
Associated microRNA: hsa-miR-942-5p
Biological function: Knockdown of hsa_circ_0001681 significantly repressed the proliferation, migration, invasion and EMT of TC cells
Molecular mechanism: through targeting hsa-miR-942-5p/TWIST1 signaling pathway
Survival: -
Supported No.:
 1
Description:

silencing of hsa_circ_0001681 significantly suppressed TC progression through inhibiting EMT via acting as a miR-942-5p sponge to facilitate the expression of TWIST1.
Other information
Title:

Downregulation of hsa_circ_0001681 suppresses epithelial-mesenchymal transition in thyroid carcinoma via targeting to miR-942-5p/TWIST1 signaling pathway.

Journal: J Bioenerg Biomembr
Published: 2021/6/25
PubMed ID: 34164767