circRNA basic information
circBase ID: -
Name: hsa_circ_CSPP1
Synonym: -
Host Gene: hsa-miR-577
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: HCC cell lines (SK-HEP-1, HCCLM3, MHCC97L, Huh7, Hep3B), human liver cell line (LO2)
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: CCNE2
Associated microRNA: hsa-miR-577
Biological function: -
Molecular mechanism: miRNA sponge
Survival: poor
Supported No.:
 6
Description:

circ-CSPP1 contributed to HCC progression by positively regulating CCNE2 via miR-577, thus established its potential as new a prognostic and therapeutic marker for HCC patients.
Other information
Title:

Circular RNA circ-CSPP1 regulates CCNE2 to facilitate hepatocellular carcinoma cell growth via sponging miR-577.

Journal: Cancer Cell Int
Published: 2020/6/10
PubMed ID: 32514247