circRNA basic information
circBase ID: hsa_circ_0018534
Name: hsa_circ_SLC25A16
Synonym: -
Host Gene: hsa-miR-488-3p
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human normal bronchial epithelial cells (NHBE), NSCLC cell lines (H460, H1299, A549)
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: HIF-1alpha/LDHA
Associated microRNA: hsa-miR-488-3p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: poor
Supported No.:
 1
Description:

the crucial function of circSLC25A16 on NSCLC glycolysis through miR-488-3p/HIF-1alpha/LDHA, suggesting the underlying pathogenesis for NSCLC and providing a therapeutic strategy for precise treatment.
Other information
Title:

Circular RNA circSLC25A16 contributes to the glycolysis of non-small-cell lung cancer through epigenetic modification.

Journal: Cell Death Dis
Published: 2020/6/10
PubMed ID: 32513983