circRNA basic information
circBase ID: hsa_circ_0022812
Name: hsa_circ_POLA2
Synonym: -
Host Gene: hsa-miR-326
 
 
 
Disease basic information
DO ID:
 1324
DO name: lung cancer
Disease details: lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human lung cancer cell lines (H1770, A549, H1975, H596, H1299, H1650), normal lung epithelial cell line (BEAS2B)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: GNB1
Associated microRNA: hsa-miR-326
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

circ_POLA2 promotes lung cancer cell stemness and progression via regulating the miR-326/GNB1 axis, which might serve as a novel therapeutic target for lung cancer patients.
Other information
Title:

CircRNA circ_POLA2 promotes lung cancer cell stemness via regulating the miR-326/GNB1 axis.

Journal: Environ Toxicol
Published: 2020/6/9
PubMed ID: 32511866