circRNA basic information
circBase ID: hsa_circ_0004214
Name: hsa_circ_AMOTL1
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
 1324
DO name: lung cancer
Disease details: lung cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: HaCaT, MCF-10A
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: c-myc
Associated microRNA: -
Biological function: promotes tumorigenesis
Molecular mechanism: inducing c-myc nuclear translocation
Survival: -
Supported No.:
 1
Description:

Expression of circ-Amotl1 was analyzed in a variety of cell lines by real-time PCR. Nine cancer cell lines expressed higher levels of circ-Amotl1 relative to two non-cancer cell lines HaCaTand MCF-10A.
Other information
Title:

A circular RNA promotes tumorigenesis by inducing c-myc nuclear translocation.

Journal: Cell Death Differ
Published: 2017/6/18
PubMed ID: 28622299