circRNA basic information
circBase ID: hsa_circ_0008532
Name: hsa_circ_CBFA2T2
Synonym: -
Host Gene: hsa-miR-155-5p, hsa-miR-330-5p
 
 
 
Disease basic information
DO ID:
11054
DO name: urinary bladder cancer
Disease details: bladder cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: uroepithelial cell (SV-HUC-1), bladder cancer cell lines (5637, UM-UC-3, TCCSUP, T24, EJ, SCaBER, T24T, J82, SW780)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: MTGR1
Associated microRNA: hsa-miR-155-5p, hsa-miR-330-5p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
1
Description:

Circ_0008532 may act as an oncogene in BC through a novel circ_0008532/miR-155-5p, miR-330-5p /MTGR1/Notch pathway axis, which in turn may provide potential biomarkers and a therapeutic target for the management of bladder cancer.

Other information
Title:

Circ_0008532 promotes bladder cancer progression by regulation of the miR-155-5p/miR-330-5p/MTGR1 axis.

Journal: J Exp Clin Cancer Res
Published: 2020/5/29
PubMed ID: 32460831