circRNA basic information
circBase ID: -
Name: hsa_circ_TUBGCP3
Synonym: -
Host Gene: hsa-miR-30b
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human osteosarcoma cell lines (143B, HOS, U20S, MG-63), HEK-293, human osteoblast cells hFOB1.19
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: Vimentin
Associated microRNA: hsa-miR-30b
Biological function: Promotes Cell Proliferation, Migration and Survivability
Molecular mechanism: act as a sponge of hsa-miR-30b that further alters the expression of Vimentin
Survival: -
Supported No.:
 2
Description:

The data indicate that circTUBGCP3 may act as a sponge of miR-30b that further alters the expression of Vimentin, and promotes the proliferation and metastatic properties of OS cells.

Other information
Title:

Circular RNA circTUBGCP3 Is Up-Regulated and Promotes Cell Proliferation, Migration and Survivability via Sponge _mir-30b in Osteosarcoma.

Journal: Onco Targets Ther
Published: 2020/5/23
PubMed ID: 32440142