circRNA basic information
circBase ID: hsa_circ_0007142
Name: -
Synonym: circ_0007142
Host Gene: hsa-miR-122-5p
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: CRC cell lines (HT-29, HCT-116), human normal colorectal epithelial cell line (NCM460)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: CDC25A
Associated microRNA: hsa-miR-122-5p
Biological function: Circ_0007142 knockdown impeded cell proliferation, colony formation, migration, and invasion in CRC cells
Molecular mechanism: sponged hsa-miR-122-5p and CDC25A was a target of hsa-miR-122-5p
Survival: -
Supported No.:
 3
Description:

Circ_0007142 sponged miR-122-5p and CDC25A was a target of miR-122-5p. Circ_0007142 knockdown impeded cell proliferation, colony formation, migration, and invasion in CRC cells by regulating miR-122-5p.

Other information
Title:

Circular RNA circ_0007142 Facilitates Colorectal Cancer Progression by Modulating CDC25A Expression via miR-122-5p.

Journal: Onco Targets Ther
Published: 2020/5/21
PubMed ID: 32431519