circRNA basic information
circBase ID: hsa_circ_0001368
Name: -
Synonym: circ_0001368
Host Gene: hsa-miR-492
 
 
 
Disease basic information
DO ID:
 4451
DO name: renal carcinoma
Disease details: renal carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: renal cell carcinoma lines (786-O, ACHN, A498), normal cell line (HEK-293)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: LATS2
Associated microRNA: hsa-miR-492
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

circ_0001368 upregulated the LATS2 expression and suppressed ACHN and 786-O cell growth and invasion by sponging miR-492. circ_0001368 suppressed the proliferation ability of 786-O in vivo.

Other information
Title:

Circular RNA circ_0001368 inhibited growth and invasion in renal cell carcinoma by sponging miR-492 and targeting LATS2.

Journal: Gene
Published: 2020/5/20
PubMed ID: 32428698