circRNA basic information
circBase ID: -
Name: hsa_circ_KIF4A
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human BC cells (MCF-7, MDA-MB-231), human mammary gland epithelial cells (MCF-10A)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: promotes cell migration, invasion and inhibits apoptosis
Molecular mechanism: through hsa-miR-152/ZEB1 axis
Survival: -
Supported No.:
 4
Description:

Silencing of circKIF4A hampered cell metastasis and promoted apoptosis by regulating ZEB1 via sponging miR-152 in BC.
Other information
Title:

Circular RNA KIF4A promotes cell migration, invasion and inhibits apoptosis through miR-152/ZEB1 axis in breast cancer.

Journal: Diagn Pathol
Published: 2020/5/16
PubMed ID: 32408908