circRNA basic information
circBase ID: -
Name: hsa_circ_CCDC9
Synonym: -
Host Gene: hsa-miR-6792-3p
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: normal human gastric epithelial mucosa cell line (GES-1), human GC cell lines (AGS, BGC-823, HGC-27, MGC-803, MKN-28, MKN-45, SGC-7901)
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
DN
Associated gene: CAV1
Associated microRNA: hsa-miR-6792-3p
Biological function: inhibited the proliferation, migration and invasion of GC cell lines in vitro and tumor growth and metastasis in vivo
Molecular mechanism: through hsa-miR-6792-3p/CAV1 axis
Survival: better
Supported No.:
 1
Description:

CircCCDC9 functions as a tumor suppressor in inhibiting the progression of GC through miR-6792-3p/CAV1 axis, which has provided an exploitable biomarker and therapeutic target for patients with GC.
Other information
Title:

Circular RNA circCCDC9 acts as a miR-6792-3p sponge to suppress the progression of gastric cancer through regulating CAV1 expression.

Journal: Mol Cancer
Published: 2020/5/11
PubMed ID: 32386516