circRNA basic information
circBase ID: -
Name: -
Synonym: circ9119
Host Gene: hsa-miR-126
 
 
 
Disease basic information
DO ID:
 4362
DO name: cervical cancer
Disease details: cervical cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: CC cells (HeLa, U14, SiHa, CaSki), normal cervical epithelial H8 cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: MDM4
Associated microRNA: hsa-miR-126
Biological function: silencing of circ9119 or the upregulation of miR-126 resulted in suppressed proliferation, accompanied by the induced apoptosis of CC cells
Molecular mechanism: functioned as an hsa-miR-126 ceRNA to increase MDM4 expression
Survival: -
Supported No.:
 1
Description:

Our findings demonstrated that circ9119 acts as an oncogene in CC. Our study provides evidence for targeting circ9119 for the treatment of CC.
Other information
Title:

CircularRNA-9119 promotes the proliferation of cervical cancer cells by sponging miR-126/MDM4.

Journal: Mol Cell Biochem
Published: 2020/5/10
PubMed ID: 32385717