circRNA basic information
circBase ID: -
Name: rno_circ_DMNT3B
Synonym: circDMNT3B
Host Gene: rno-miR-20b-5p
 
 
 
Disease basic information
DO ID:
 0040085
DO name: bacterial sepsis
Disease details: sepsis
Species: rat
Species details: rat
Sample type: tissue, cell line
Sample type details: HEK-293T cells and Caco2 cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: SOD
Associated microRNA: rno-miR-20b-5p
Biological function: Silencing circDNMT3B decreased cell survival and induced apoptosis
Molecular mechanism: -
Survival: -
Supported No.:
 1
Description:

Down-regulation of circDMNT3B was conducive to the dysfunction of intestinal mucosal permeability via sponging miR-20b-5p in sepsis rats, which may provide the novel strategy for sepsis treatment in the future
Other information
Title:

Down-regulation of circDMNT3B is conducive to intestinal mucosal permeability dysfunction of rats with sepsis via sponging miR-20b-5p.

Journal: J Cell Mol Med
Published: 2020/5/10
PubMed ID: 32383354