circRNA basic information
circBase ID: hsa_circ_0020710
Name: -
Synonym: circ_0020710
Host Gene: hsa-miR-370-3p
 
 
 
Disease basic information
DO ID:
 1909
DO name: melanoma
Disease details: melanoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: A375, A2058, A875, Sk-mel-28, MV3, M14 (melanoma cell lines), HaCaT (normal epidermal cell line), HEK-293_T cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: CXCL12
Associated microRNA: hsa-miR-370-3p
Biological function: promoted melanoma cell proliferation, migration and invasion
Molecular mechanism: upregulate the CXCL12 expression via sponging hsa-miR-370-3p
Survival: -
Supported No.:
 1
Description:

Elevated circ_0020710 drives tumor progression via the miR-370-3p/CXCL12 axis, and circ_0020710 is a potential target for melanoma treatment.
Other information
Title:

Circular RNA circ_0020710 drives tumor progression and immune evasion by regulating the miR-370-3p/CXCL12 axis in melanoma.

Journal: Mol Cancer
Published: 2020/5/10
PubMed ID: 32381016