circRNA basic information
circBase ID: hsa_circ_0017639
Name: hsa_circ_SFMBT2
Synonym: -
Host Gene: hsa-miR-224-5p
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human GC cell lines (SGC-7901, MGC-803, MKN-28, BGC823), gastric epithelial cell (GES-1)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: USP3
Associated microRNA: hsa-miR-224-5p
Biological function: promotes gastric cancer proliferation and metastasis
Molecular mechanism: sponging hsa-miR-224-5p and upregulating USP3
Survival: -
Supported No.:
 4
Description:

hsa_circ_0017639 takes part in GC progression through regulating the miR-224-5p/USP3 axis, highlighting its potential as an effective GC therapeutic target.
Other information
Title:

Hsa_circ_0017639 expression promotes gastric cancer proliferation and metastasis by sponging miR-224-5p and upregulating USP3.

Journal: Gene
Published: 2020/5/8
PubMed ID: 32376451