circRNA basic information
circBase ID: -
Name: hsa_circ_HMCU
Synonym: -
Host Gene: hsa-let-7
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human breast cancer cells (MDA-MB-231, MDA-MB-468, MCF7)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: MCY, HMGA2, and CCND1
Associated microRNA: hsa-let-7
Biological function: Promotes Proliferation and Metastasis
Molecular mechanism: Sponging the let-7
Survival: poor
Supported No.:
 2
Description:

circHMCU exerted oncogenic functions in breast cancer and could be a used as a novel biomarker in the diagnosis and prognosis of breast cancer.
Other information
Title:

circHMCU Promotes Proliferation and Metastasis of Breast Cancer by Sponging the let-7 Family.

Journal: Mol Ther Nucleic Acids
Published: 2020/4/25
PubMed ID: 32330870