circRNA basic information
circBase ID: -
Name: hsa_circ_EPB41L2
Synonym: -
Host Gene: hsa-miR-211-5p
 
 
 
Disease basic information
DO ID:
 1324
DO name: lung cancer
Disease details: lung cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human bronchial epithelial cell line (HBE), LUAD cell lines (A549, HCC827, H460, Calu-3)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: CDH4
Associated microRNA: hsa-miR-211-5p
Biological function: inhibit the proliferation, migration and invasion
Molecular mechanism: regulating CDH4 by hsa-miR-211-5p
Survival: -
Supported No.:
 2
Description:

Circ_EPB41L2 functioned as a tumor suppressor to inhibit the proliferation, migration and invasion through regulating CDH4 by miR-211-5p in LUAD cells, suggesting a new understanding on the tumorigenesis of LUAD and novel molecular therapeutic targets.
Other information
Title:

CircRNA EPB41L2 inhibits tumorigenicity of lung adenocarcinoma through regulating CDH4 by miR-211-5p.

Journal: Eur Rev Med Pharmacol Sci
Published: 2020/4/25
PubMed ID: 32329852