circRNA basic information
circBase ID: hsa_circ_0091074
Name: hsa_circ_TCONS_00016926
Synonym: -
Host Gene: hsa-miR-1297
 
 
 
Disease basic information
DO ID:
 60081
DO name: triple-receptor negative breast cancer
Disease details: triple-negative breast cancer
Species: human
Species details: human
Sample type: cell line
Sample type details: human breast cancer cell lines (MDA-MB-231, MCF-7, MDA-MB-468)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: TAZ
Associated microRNA: hsa-miR-1297
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

The current results indicate that miR_1297 serves as a suppressor of breast cancer cell proliferation and invasiveness, and that this can be partially reversed by hsa_circ_0091074, suggesting that the hsa_circ_0091074/miR_1297/TAZ/TEAD4 axis may represent a potential therapeutic target for triple negative breast cancer in the future.
Other information
Title:

Hsa_circ_0091074 regulates TAZ expression via microRNA_1297 in triple negative breast cancer cells.

Journal: Int J Oncol
Published: 2020/4/23
PubMed ID: 32319577