circRNA basic information
circBase ID: hsa_circ_0072309
Name: -
Synonym: hsa_circ_0072309
Host Gene: hsa-miR-580-3p
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: normal human bronchial epithelial cell line (HBE), human NSCLC cells lines (CALU3, H125, A549, H1299)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-580-3p
Biological function: suppressed the cell proliferation, migration and invasion
Molecular mechanism: sponging hsa-miR-580-3p
Survival: -
Supported No.:
 3
Description:

These data showed that circ_0072309 inhibits the progression of NSCLC progression via blocking the expression of miR-580-3p. These findings revealed the anti-tumor role of circ_0072309 during the development of NSCLC and provided a novel diagnostic biomarker and potential therapy for NSCLC.
Other information
Title:

Circular RNA hsa_circ_0072309 inhibits non-small cell lung cancer progression by sponging miR-580-3p.

Journal: Biosci Rep
Published: 2020/4/16
PubMed ID: 32293004