circRNA basic information
circBase ID: -
Name: -
Synonym: hsa_circ_100338
Host Gene: hsa-miR-141-3p
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: HCC cell lines (HepG2, HuH_7), human normal liver cell line (HL_7702)
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: ZEB1
Associated microRNA: hsa-miR-141-3p
Biological function: promoting the progression of HCC
Molecular mechanism: sponging hsa-miR-141-3p
Survival: -
Supported No.:
 1
Description:

circ-100338 played as a ceRNA in promoting the progression of HCC by sponging miR-141-3p, while piplartine can participate in the development of HCC by inhibiting the expression of circ-100338.
Other information
Title:

Piplartine attenuates the proliferation of hepatocellular carcinoma cells via regulating hsa_circ_100338 expression.

Journal: Cancer Med
Published: 2020/4/14
PubMed ID: 32281302