circRNA basic information
circBase ID: hsa_circ_0031288
Name: hsa_circ_PABPN1
Synonym: -
Host Gene: hsa-miR-139-3p
 
 
 
Disease basic information
DO ID:
 4362
DO name: cervical cancer
Disease details: cervical cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: HeLa, C4_1, SHa, Cuski, H8, 293T
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: Bcl-6
Associated microRNA: hsa-miR-139-3p
Biological function: promote the migration, invasion, proliferation, and growth of xenograft and HeLa cells
Molecular mechanism: Hsa_circ_0031288/hsa-miR-139-3p/Bcl-6 regulatory feedback circuit
Survival: -
Supported No.:
 2
Description:

the hsa_circ_0031288/hsa-miR-139-3p/Bcl-6 regulatory axis affects cell migration and proliferation, and its mechanism may involve hsa_circ_0031288 acting as a sponge for hsa-miR-139-3p, thereby relieving the transcriptional inhibition of Bcl-6.
Other information
Title:

Hsa_circ_0031288/hsa-miR-139-3p/Bcl-6 regulatory feedback circuit influences the invasion and migration of cervical cancer HeLa cells.

Journal: J Cell Biochem
Published: 2020/4/12
PubMed ID: 32277518