circRNA basic information
circBase ID: hsa_circ_0060745
Name: -
Synonym: circ_0060745
Host Gene: hsa-miR-4736
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: A human colon epithelial cell line (NCM460), four human CRC cell lines (HT29, LOVO, PKO, SW480)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: CSE1L
Associated microRNA: hsa-miR-4736
Biological function: Promotes Colorectal Cancer Cell Proliferation and Metastasis
Molecular mechanism: Circ_0060745/hsa-miR-4736/CSE1L axis
Survival: -
Supported No.:
 1
Description:

circ_0060745 promoted CRC cell proliferation and metastasis via modulation of miR-4736/CSE1L signaling. The Circ_0060745/miR-4736/CSE1L axis might be a novel target for the treatment of CRC.
Other information
Title:

Circular RNA 0060745, a Novel circRNA, Promotes Colorectal Cancer Cell Proliferation and Metastasis Through miR-4736 Sponging.

Journal: Onco Targets Ther
Published: 2020/4/11
PubMed ID: 32273712