circRNA basic information
circBase ID: -
Name: hsa_circ_ACACA
Synonym: circ-ACACA
Host Gene: hsa-miR-1183
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human normal bronchus epithelium cell line (BEAS-2B), NSCLC cell lines (A549, H1975, H1395, H1793, H1299, H1792)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: PI3K/PKB pathway
Associated microRNA: hsa-miR-1183
Biological function: promoted proliferation, migration
Molecular mechanism: regulated the PI3K/PKB pathway through interacting with miR_1183
Survival: -
Supported No.:
 3
Description:

circ_ACACA regulated the PI3K/PKB pathway through interacting with miR_1183 and downregulation of circ_ACACA suppressed tumor growth.
Other information
Title:

Circular RNA circ_ACACA regulates proliferation, migration and glycolysis in non_small_cell lung carcinoma via miR_1183 and PI3K/PKB pathway.

Journal: Int J Mol Med
Published: 2020/4/3
PubMed ID: 32236577