circRNA basic information
circBase ID: -
Name: hsa_circ_CCDC66
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human gastric cancer cell lines (BGC-823, MGC-803, SGC-7901, HGC-27)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: c-Myc EMT and TGF-beta signaling pathways
Associated microRNA: -
Biological function: promotes GC growth and metastasis
Molecular mechanism: activating c-Myc and TGF-beta signaling pathways
Survival: poor
Supported No.:
 2
Description:

CircCCDC66 promotes GC growth and metastasis by activating c-Myc and TGF-beta signaling pathways, suggesting that it may serve as a potential biomarker for GC.
Other information
Title:

Circular RNA CCDC66 promotes gastric cancer progression by regulating c-Myc and TGF-beta signaling pathways.

Journal: J Cancer
Published: 2020/4/1
PubMed ID: 32226494