circRNA basic information
circBase ID: hsa_circ_0001649
Name: hsa_circ_SHPRH
Synonym: -
Host Gene: hsa-miR-20a
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: SGC_7901, AGS, MKN28, MKN28, MKN45, GES_1
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: ERK and Wnt/beta-catenin pathways
Associated microRNA: hsa-miR-20a
Biological function: restrained viability, proliferation, migration, and invasion, while promoted apoptosis
Molecular mechanism: downregulation of hsa-miR-20a
Survival: -
Supported No.:
 2
Description:

Upregulation of hsa_circ_0001649 restrained GC cell growth and metastasis by downregulating miR-20a and thereby inactivated ERK and Wnt/beta-catenin pathways.
Other information
Title:

Hsa_circ_0001649 restrains gastric carcinoma growth and metastasis by downregulation of miR-20a.

Journal: J Clin Lab Anal
Published: 2020/3/27
PubMed ID: 32212290