circRNA basic information
circBase ID: hsa_circ_0008717
Name: hsa_circ_ABCB10
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human NSCLC cell lines (A549, SPCA1, PC9, H1299), normal human bronchial epithelial cell (16HBE)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: KISS1
Associated microRNA: -
Biological function: promotes non-small cell lung cancer proliferation and inhibits cell apoptosis
Molecular mechanism: repressing KISS1
Survival: -
Supported No.:
 4
Description:

Results above indicated that circ-ABCB10 promoted cell proliferation and inhibited cell apoptosis of NSCLC by suppressing KISS1, which suggested that circ-ABCB10 may be a potential therapeutic target in NSCLC.
Other information
Title:

Circular RNA circ-ABCB10 promotes non-small cell lung cancer proliferation and inhibits cell apoptosis through repressing KISS1.

Journal: Eur Rev Med Pharmacol Sci
Published: 2020/3/21
PubMed ID: 32196602