circRNA basic information
circBase ID: hsa_circ_0008225
Name: hsa_circ_ZMYND11
Synonym: -
Host Gene: hsa-miR-890
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human cortical astrocytes cell line (HA1800), human glioblastoma cell line (U87MG, U251MG, SHG-44)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: ZMYND11
Associated microRNA: hsa-miR-890
Biological function: inhibits tumorigenesis of glioma
Molecular mechanism: sponging hsa-miR-890 and promoting ZMYND11 expression
Survival: better
Supported No.:
 1
Description:

Our results suggested that hsa_circ_0008225 functions as a tumor inhibitor in glioma by sponging miR-890 and then promoting the function of ZMYND11. Therefore, hsa_circ_0008225 could be a potential prognostic biomarker for the treatment of glioma.
Other information
Title:

Hsa_circ_0008225 inhibits tumorigenesis of glioma via sponging miR-890 and promoting ZMYND11 expression.

Journal: J Pharmacol Sci
Published: 2020/3/21
PubMed ID: 32192854