circRNA basic information
circBase ID: -
Name: hsa_circ_PITX1
Synonym: -
Host Gene: hsa-miR-329-3p
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: normal human astrocyte (NHA), human glioma cells (U251)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: NEK2
Associated microRNA: hsa-miR-329-3p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 2
Description:

CircPITX1 knockdown reduced glycolysis to contribute to radiosensitivity in glioma through miR-329-3p/NEK2 axis, providing a possible mechanism of circPITX1 in the development of glioma.
Other information
Title:

Circular RNA circPITX1 knockdown inhibits glycolysis to enhance radiosensitivity of glioma cells by miR-329-3p/NEK2 axis.

Journal: Cancer Cell Int
Published: 2020/3/20
PubMed ID: 32190004