circRNA basic information
circBase ID: hsa_circ_0068033
Name: hsa_circ_NAALADL2
Synonym: -
Host Gene: hsa-miR-659
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: BC cell lines (MCF10A, MCF-7, T47D, MDA-MB-468)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-659
Biological function: inhibit the growths, clone formation, invasion and migration of MCF-7 and MDA-MB-231 cells while activating the intrinsic apoptotic pathway to induce apoptosis.
Molecular mechanism: Sponging hsa-miR-659
Survival: better
Supported No.:
 2
Description:

hsa_circ_0068033 acts as a tumor suppressor gene in BC, and the hsa_circ_0068033/miR-659 axis participates in the progression of BC.
Other information
Title:

Circular RNA hsa_circ_0068033 Acts as a Diagnostic Biomarker and Suppresses the Progression of Breast Cancer Through Sponging miR-659.

Journal: Onco Targets Ther
Published: 2020/3/19
PubMed ID: 32184627