circRNA basic information
circBase ID: hsa_circ_0058063
Name: hsa_circ_ATIC
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
 11054
DO name: urinary bladder cancer
Disease details: bladder cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: BC cell lines (BIU-87, 5637, RT-112)
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: promote cell proliferation and invasion, and suppress apoptosis
Molecular mechanism: regulated FOXP4 expression by competitively binding to hsa-miR-486-3p
Survival: -
Supported No.:
 3
Description:

circRNA_0058063 functions by sponging miR-486-3p in BC progression, which could act as a new biomarker and further developed to be a therapeutic target in BC.
Other information
Title:

CircRNA_0058063 functions as a ceRNA in bladder cancer progression via targeting miR-486-3p/FOXP4 axis.

Journal: Biosci Rep
Published: 2020/3/18
PubMed ID: 32181485