circRNA basic information
circBase ID: hsa_circ_0000384
Name: hsa_circ_MRPS35
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: AGS, HGC27, GES-1, MKN45, MKN74, MKN28
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
DN
Associated gene: KAT7/FOXO1/3a
Associated microRNA: -
Biological function: suppresses the proliferation and invasion
Molecular mechanism: circMRPS35/KAT7/FOXO1/3a pathway
Survival: -
Supported No.:
2
Description:

Our findings not only reveal the pivotal roles of circMRPS35 in governing histone modification in anticancer treatment, but also advocate for triggering circMRPS35/KAT7/FOXO1/3a pathway to combat gastric cancer.

Other information
Title:

CircMRPS35 suppresses gastric cancer progression via recruiting KAT7 to govern histone modification.

Journal: Mol Cancer
Published: 2020/3/14
PubMed ID: 32164722