circRNA basic information
circBase ID: hsa_circ_0007843
Name: hsa_circ_ARHGAP32
Synonym: -
Host Gene: hsa-miR-518c-5p
 
 
 
Disease basic information
DO ID:
 219
DO name: colon cancer
Disease details: colon cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: 293T, FIHC, HCT-116, HT-29, SW480, LOVO, SW620
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: MMP2
Associated microRNA: hsa-miR-518c-5p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

hsa_circ_0007843 acted as an miRNA sponge to regulate MMP2 expression by removing the inhibitory effect of miR-518c-5p on MMP2 gene translation, which further affected the invasive capability of SW480 cells.
Other information
Title:

Hsa_Circ_0007843 Acts as a mIR-518c-5p Sponge to Regulate the Migration and Invasion of Colon Cancer SW480 Cells.

Journal: Front Genet
Published: 2020/3/12
PubMed ID: 32158464