circRNA basic information
circBase ID: hsa_circ_0049487
Name: hsa_circ_CNN1
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Survival: -
Supported No.:
 1
Description:

Receiver operating characteristic (ROC) curve analysis identified three circRNAs (hsa_circ_0049487, hsa_circ_0066875, and hsa_circ_0007444) as possible novel biomarkers predicting the transition from colonic adenoma to cancer. Overall, our findings may provide novel perspectives to clarify the mechanisms of the transition from premalignant adenoma to cancer and identify specific circRNA-related signatures with possible applications for the early diagnosis of and as potential therapeutic targets in CRC.
Other information
Title:

Comprehensive RNA Sequencing in Adenoma-Cancer Transition Identified Predictive Biomarkers and Therapeutic Targets of Human CRC.

Journal: Mol Ther Nucleic Acids
Published: 2020/3/8
PubMed ID: 32145677