circRNA basic information
circBase ID: hsa_circ_0000284
Name: hsa_circ_HIPK3
Synonym: -
Host Gene: hsa-miR-107
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: normal human gastric epithelial cell line (GES-1), GC cell lines (SGC-7901, MKN45, MGC-803, AGS, BGC-823)
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: BDNF
Associated microRNA: hsa-miR-107
Biological function: Promotes Cell Proliferation and Migration
Molecular mechanism: miRNA sponge
Survival: poor
Supported No.:
 6
Description:

circHIPK3 was identified as a sponge of miR-107, and as such it regulated brain-derived neurotrophic factor (BDNF), which plays a pivotal role in the development of GC.
Other information
Title:

circHIPK3 Promotes Cell Proliferation and Migration of Gastric Cancer by Sponging miR-107 and Regulating BDNF Expression.

Journal: Onco Targets Ther
Published: 2020/2/29
PubMed ID: 32110057