circRNA basic information
circBase ID: hsa_circ_0001946
Name: hsa_circ_CDR1
Synonym: ciRS-7, CDR1as
Host Gene: hsa-miR-641
 
 
 
Disease basic information
DO ID:
 8398
DO name: osteoarthritis
Disease details: osteoarthritis
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: MMP13 and IL-6
Associated microRNA: hsa-miR-641
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 2
Description:

our results indicate that circRNA-CDR1as plays a crucial role in regulating OA progression via modulating extracellular matrix metabolism and inflammation via sponging miR-641 and provide a novel regulatory role of circRNA-CDR1as in OA.
Other information
Title:

Circular RNA-CDR1as acts as the sponge of microRNA-641 to promote osteoarthritis progression.

Journal: J Inflamm (Lond)
Published: 2020/2/27
PubMed ID: 32099534